7W2Z
Cryo-EM structure of the ghrelin-bound human ghrelin receptor-Go complex
Summary for 7W2Z
Entry DOI | 10.2210/pdb7w2z/pdb |
EMDB information | 32268 |
Descriptor | Guanine nucleotide-binding protein G(o) subunit alpha, Growth hormone secretagogue receptor type 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, ghrelin, endogenous agonist, class a gpcr, peptide receptor, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 142349.50 |
Authors | |
Primary citation | Qin, J.,Cai, Y.,Xu, Z.,Ming, Q.,Ji, S.Y.,Wu, C.,Zhang, H.,Mao, C.,Shen, D.D.,Hirata, K.,Ma, Y.,Yan, W.,Zhang, Y.,Shao, Z. Molecular mechanism of agonism and inverse agonism in ghrelin receptor. Nat Commun, 13:300-300, 2022 Cited by PubMed: 35027551DOI: 10.1038/s41467-022-27975-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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