7W2D

The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with S1RA

7W2D の概要

• エントリーDOI: 10.2210/pdb7w2d/pdb
• 分子名称: Sigma non-opioid intracellular receptor 1, GOLD ION, 4-[2-(5-methyl-1-naphthalen-2-yl-pyrazol-3-yl)oxyethyl]morpholine (3 entities in total)
• 機能のキーワード: sigma receptor, membrane receptor, s1r, ligand entry, membrane protein
• 由来する生物種: Xenopus laevis (African clawed frog)
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 310236.38

構造登録者

Meng, F.,Sun, Z.,Zhou, X. (登録日: 2021-11-23, 公開日: 2022-03-16, 最終更新日: 2023-11-29)

• 主引用文献: Meng, F.,Xiao, Y.,Ji, Y.,Sun, Z.,Zhou, X.; An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.; Nat Commun, 13:1267-1267, 2022; PubMed: 35273182; DOI: 10.1038/s41467-022-28946-w

実験手法

X-RAY DIFFRACTION (3.471 Å)