7VZF

Cryo-EM structure of amyloid fibril formed by full-length human SOD1

Summary for 7VZF

Entry DOI	10.2210/pdb7vzf/pdb
EMDB information	32227
Descriptor	Superoxide dismutase [Cu-Zn] (1 entity in total)
Functional Keywords	amyloid fibril, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	47876.27
Authors	Wang, L.Q.,Ma, Y.Y.,Yuan, H.Y.,Zhao, K.,Zhang, M.Y.,Wang, Q.,Huang, X.,Xu, W.C.,Chen, J.,Li, D.,Zhang, D.L.,Zou, L.Y.,Yin, P.,Liu, C.,Liang, Y. (deposition date: 2021-11-16, release date: 2022-06-29, Last modification date: 2024-06-26)
Primary citation	Wang, L.Q.,Ma, Y.,Yuan, H.Y.,Zhao, K.,Zhang, M.Y.,Wang, Q.,Huang, X.,Xu, W.C.,Dai, B.,Chen, J.,Li, D.,Zhang, D.,Wang, Z.,Zou, L.,Yin, P.,Liu, C.,Liang, Y. Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion. Nat Commun, 13:3491-3491, 2022 Cited by PubMed: 35715417 DOI: 10.1038/s41467-022-31240-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.95 Å)

Structure validation