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7VWG

Human peroxisome proliferator-activated receptor (PPAR) delta ligand binding domain in complex with a synthetic alpha/delta dual agonist JKPL38

Summary for 7VWG
Entry DOI10.2210/pdb7vwg/pdb
DescriptorPeroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside, (2S)-2-[[4-propoxy-3-[[[4-(trifluoromethyl)phenyl]carbonylamino]methyl]phenyl]methyl]butanoic acid, ... (4 entities in total)
Functional Keywordsnuclear receptor, protein-ligand complex, ppar, transcription
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight64486.88
Authors
Oyama, T.,Miyachi, H. (deposition date: 2021-11-10, release date: 2022-02-09, Last modification date: 2023-11-29)
Primary citationOyama, T.,Takiguchi, K.,Miyachi, H.
Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor delta in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative.
Acta Crystallogr.,Sect.F, 78:81-87, 2022
Cited by
DOI: 10.1107/S2053230X22000449
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

221051

건을2024-06-12부터공개중

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