7VWF

Human peroxisome proliferator-activated receptor (PPAR) delta ligand binding domain in complex with a synthetic agonist TIPP204

Summary for 7VWF

Entry DOI	10.2210/pdb7vwf/pdb
Descriptor	Peroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside, (2S)-2-{4-butoxy-3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]benzyl}butanoic acid, ... (4 entities in total)
Functional Keywords	nuclear receptor, protein-ligand complex, ppar, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	64550.92
Authors	Oyama, T.,Miyachi, H. (deposition date: 2021-11-10, release date: 2022-02-09, Last modification date: 2023-11-29)
Primary citation	Oyama, T.,Takiguchi, K.,Miyachi, H. Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor delta in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative. Acta Crystallogr.,Sect.F, 78:81-87, 2022 Cited by DOI: 10.1107/S2053230X22000449 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation