7VUP

Structure of NF-kB p52 homodimer bound to +1/-1 swap P-Selectin kB DNA fragment

7VUP の概要

• エントリーDOI: 10.2210/pdb7vup/pdb
• 分子名称: Nuclear factor NF-kappa-B p52 subunit, DNA (5'-D(*CP*AP*AP*GP*GP*GP*GP*AP*CP*TP*CP*CP*CP*CP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*GP*GP*GP*GP*GP*AP*GP*TP*CP*CP*CP*CP*TP*TP*G)-3') (3 entities in total)
• 機能のキーワード: dna-protein complex, transcription factor, transcription, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 98500.13

構造登録者

Meshcheryakov, V.A.,Wang, V.Y.-F. (登録日: 2021-11-04, 公開日: 2021-11-24, 最終更新日: 2023-11-29)

• 主引用文献: Pan, W.,Meshcheryakov, V.A.,Li, T.,Wang, Y.,Ghosh, G.,Wang, V.Y.; Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.; Elife, 12:-, 2023; PubMed: 36779700; DOI: 10.7554/eLife.86258

実験手法

X-RAY DIFFRACTION (3.4 Å)