7VUE
Structural insight of the molecular mechanism of cilofexor bound to FXR
Summary for 7VUE
Entry DOI | 10.2210/pdb7vue/pdb |
Descriptor | Bile acid receptor, Peptide from Nuclear receptor coactivator 2, 2-[3-[4-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-2-chloranyl-phenyl]-3-oxidanyl-azetidin-1-yl]pyridine-4-carboxylic acid, ... (4 entities in total) |
Functional Keywords | nuclear receptor, ligand binding, nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 28742.19 |
Authors | Jiang, L.,Chen, Y.C. (deposition date: 2021-11-02, release date: 2022-03-16, Last modification date: 2023-11-29) |
Primary citation | Jiang, L.,Liu, X.,Wei, H.,Dai, S.,Qu, L.,Chen, X.,Guo, M.,Chen, Y. Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor. Biochem.Biophys.Res.Commun., 595:1-6, 2022 Cited by PubMed: 35091108DOI: 10.1016/j.bbrc.2022.01.069 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.601 Å) |
Structure validation
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