7VSU

Crystal structure of Fab fragment of anti-mesothelin antibody

Summary for 7VSU

Entry DOI	10.2210/pdb7vsu/pdb
Descriptor	Light chain, heavy chain (2 entities in total)
Functional Keywords	antibody, therapeutic, biosynthetic protein
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	95806.52
Authors	Yang, Z.,Ying, T. (deposition date: 2021-10-27, release date: 2021-12-15, Last modification date: 2023-11-29)
Primary citation	Wang, C.,Hong, J.,Yang, Z.,Zhou, X.,Yang, Y.,Kong, Y.,Chen, B.,Wu, H.,Qian, B.Z.,Dimitrov, D.S.,Zhou, X.,Wu, Y.,Ying, T. Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use. Small Methods, 6:e2100966-e2100966, 2022 Cited by PubMed: 35174992 DOI: 10.1002/smtd.202100966 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation