7VPR
Crystal structure of the ligand-binding domain of C. glabrata Upc2 in complex with ergosterol
Summary for 7VPR
Entry DOI | 10.2210/pdb7vpr/pdb |
Descriptor | Sterol uptake control protein 2 (Upc2), ERGOSTEROL (3 entities in total) |
Functional Keywords | ergosterol, transcription factor, ligand-binding, zinc finger, transcription |
Biological source | [Candida] glabrata CBS 138 (Yeast, Torulopsis glabrata) |
Total number of polymer chains | 4 |
Total formula weight | 138555.47 |
Authors | |
Primary citation | Tan, L.,Chen, L.,Yang, H.,Jin, B.,Kim, G.,Im, Y.J. Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18:1253-1262, 2022 Cited by PubMed: 36229681DOI: 10.1038/s41589-022-01117-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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