7VOE
Crystal structure of 5-HT2AR in complex with aripiprazole
Summary for 7VOE
Entry DOI | 10.2210/pdb7voe/pdb |
Related | 7VOD |
Descriptor | 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, CHOLESTEROL, PENTAETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | gpcr, dopamine receptor, serotonin receptor, aripiprazole, antipsychotic, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 45255.16 |
Authors | |
Primary citation | Chen, Z.,Fan, L.,Wang, H.,Yu, J.,Lu, D.,Qi, J.,Nie, F.,Luo, Z.,Liu, Z.,Cheng, J.,Wang, S. Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties. Nat.Neurosci., 25:39-49, 2022 Cited by PubMed: 34887590DOI: 10.1038/s41593-021-00971-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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