7VKG

Crystal structure of AF9 YEATS domain in complex with Compound 10

Summary for 7VKG

• Entry DOI: 10.2210/pdb7vkg/pdb
• Descriptor: Protein AF-9, ~{N}-(4-chlorophenyl)-2-phenylmethoxy-ethanamide, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: complex, inhibitor, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16888.34

Authors

Liu, Y.,Ruan, K. (deposition date: 2021-09-29, release date: 2022-10-05, Last modification date: 2023-11-29)

• Primary citation: Liu, Y.,Jin, R.,Lu, H.,Bian, K.,Wang, R.,Wang, L.,Gao, R.,Zhang, J.,Wu, J.,Yao, X.,Liu, X.,Liu, D.,Wang, X.,Zhang, Z.,Ruan, K.; Fragment-Based Discovery of AF9 YEATS Domain Inhibitors.; Int J Mol Sci, 23:-, 2022; PubMed: 35409252; DOI: 10.3390/ijms23073893

Experimental method

X-RAY DIFFRACTION (1.83 Å)