7VIF
Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with (S)-FTY720-P
Summary for 7VIF
Entry DOI | 10.2210/pdb7vif/pdb |
EMDB information | 32007 |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, scFv16, ... (6 entities in total) |
Functional Keywords | gpcr, s1pr1, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 159113.68 |
Authors | Yu, L.Y.,Gan, B.,Xiao, Q.J.,Ren, R.B. (deposition date: 2021-09-26, release date: 2022-09-28, Last modification date: 2022-10-05) |
Primary citation | Yu, L.,He, L.,Gan, B.,Ti, R.,Xiao, Q.,Hu, H.,Zhu, L.,Wang, S.,Ren, R. Structural insights into sphingosine-1-phosphate receptor activation. Proc.Natl.Acad.Sci.USA, 119:e2117716119-e2117716119, 2022 Cited by PubMed: 35412894DOI: 10.1073/pnas.2117716119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.83 Å) |
Structure validation
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