7VFX
The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL
Summary for 7VFX
Entry DOI | 10.2210/pdb7vfx/pdb |
EMDB information | 31323 31962 |
Descriptor | fMet-Leu-Phe receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (8 entities in total) |
Functional Keywords | formyl peptide receptor 1, gi complex, signaling protein, signaling protein-protein binding complex, signaling protein/protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 160227.11 |
Authors | Wang, X.K.,Chen, G.,Liao, Q.W.,Du, Y.,Hu, H.L.,Ye, D.Q. (deposition date: 2021-09-14, release date: 2022-09-21, Last modification date: 2022-12-07) |
Primary citation | Chen, G.,Wang, X.,Liao, Q.,Ge, Y.,Jiao, H.,Chen, Q.,Liu, Y.,Lyu, W.,Zhu, L.,van Zundert, G.C.P.,Robertson, M.J.,Skiniotis, G.,Du, Y.,Hu, H.,Ye, R.D. Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns. Nat Commun, 13:5232-5232, 2022 Cited by PubMed: 36064945DOI: 10.1038/s41467-022-32822-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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