7VFX

The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL

7VFX の概要

• エントリーDOI: 10.2210/pdb7vfx/pdb
• EMDBエントリー: 31323 31962
• 分子名称: fMet-Leu-Phe receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (8 entities in total)
• 機能のキーワード: formyl peptide receptor 1, gi complex, signaling protein, signaling protein-protein binding complex, signaling protein/protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 160227.11

構造登録者

Wang, X.K.,Chen, G.,Liao, Q.W.,Du, Y.,Hu, H.L.,Ye, D.Q. (登録日: 2021-09-14, 公開日: 2022-09-21, 最終更新日: 2022-12-07)

• 主引用文献: Chen, G.,Wang, X.,Liao, Q.,Ge, Y.,Jiao, H.,Chen, Q.,Liu, Y.,Lyu, W.,Zhu, L.,van Zundert, G.C.P.,Robertson, M.J.,Skiniotis, G.,Du, Y.,Hu, H.,Ye, R.D.; Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.; Nat Commun, 13:5232-5232, 2022; PubMed: 36064945; DOI: 10.1038/s41467-022-32822-y

実験手法

ELECTRON MICROSCOPY (2.8 Å)