7VAH

The crystal structure of COVID-19 main protease in H41A mutation

Summary for 7VAH

Entry DOI	10.2210/pdb7vah/pdb
Descriptor	3C-like proteinase (2 entities in total)
Functional Keywords	protease, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	1
Total formula weight	33758.48
Authors	Liu, X.,Zhao, Y.,Yang, H.,Rao, Z. (deposition date: 2021-08-29, release date: 2022-04-06, Last modification date: 2023-11-29)
Primary citation	Zhao, Y.,Zhu, Y.,Liu, X.,Jin, Z.,Duan, Y.,Zhang, Q.,Wu, C.,Feng, L.,Du, X.,Zhao, J.,Shao, M.,Zhang, B.,Yang, X.,Wu, L.,Ji, X.,Guddat, L.W.,Yang, K.,Rao, Z.,Yang, H. Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119:e2117142119-e2117142119, 2022 Cited by PubMed: 35380892 DOI: 10.1073/pnas.2117142119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.491 Å)

Structure validation