7VAE

Cryo-EM structure of bovine NTCP complexed with YN69202Fab

7VAE の概要

• エントリーDOI: 10.2210/pdb7vae/pdb
• EMDBエントリー: 31838
• 分子名称: Solute carrier family 10 (Sodium/bile acid cotransporter family), member 1, Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202 (3 entities in total)
• 機能のキーワード: hepatitis b virus (hbv), host entry receptor, bile acid transporter, taurocholate, na+-coupled symporter, transport protein
• 由来する生物種: Bos taurus (Bovine); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 89004.08

構造登録者

Asami, J.,Shimizu, T.,Ohto, U. (登録日: 2021-08-29, 公開日: 2022-05-25, 最終更新日: 2022-07-13)

• 主引用文献: Asami, J.,Kimura, K.T.,Fujita-Fujiharu, Y.,Ishida, H.,Zhang, Z.,Nomura, Y.,Liu, K.,Uemura, T.,Sato, Y.,Ono, M.,Yamamoto, M.,Noda, T.,Shigematsu, H.,Drew, D.,Iwata, S.,Shimizu, T.,Nomura, N.,Ohto, U.; Structure of the bile acid transporter and HBV receptor NTCP.; Nature, 606:1021-1026, 2022; PubMed: 35580629; DOI: 10.1038/s41586-022-04845-4

実験手法

ELECTRON MICROSCOPY (3.55 Å)