7VAD
Cryo-EM structure of human NTCP complexed with YN69202Fab
Summary for 7VAD
Entry DOI | 10.2210/pdb7vad/pdb |
EMDB information | 31837 |
Descriptor | Sodium/bile acid cotransporter, Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202 (3 entities in total) |
Functional Keywords | hepatitis b virus (hbv), host entry receptor, bile acid transporter, taurocholate, na+-coupled symporter, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 89040.52 |
Authors | Asami, J.,Shimizu, T.,Ohto, U. (deposition date: 2021-08-29, release date: 2022-05-25, Last modification date: 2024-10-09) |
Primary citation | Asami, J.,Kimura, K.T.,Fujita-Fujiharu, Y.,Ishida, H.,Zhang, Z.,Nomura, Y.,Liu, K.,Uemura, T.,Sato, Y.,Ono, M.,Yamamoto, M.,Noda, T.,Shigematsu, H.,Drew, D.,Iwata, S.,Shimizu, T.,Nomura, N.,Ohto, U. Structure of the bile acid transporter and HBV receptor NTCP. Nature, 606:1021-1026, 2022 Cited by PubMed: 35580629DOI: 10.1038/s41586-022-04845-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.41 Å) |
Structure validation
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