7V97

Arsenic-bound p53 DNA-binding domain mutant V272M

Summary for 7V97

• Entry DOI: 10.2210/pdb7v97/pdb
• Descriptor: Cellular tumor antigen p53, ARSENIC, ZINC ION, ... (4 entities in total)
• Functional Keywords: keywords: dna-binding domain, complex, dna-bound, arsenic-bound, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 90711.91

Authors

Lu, M.,Xing, Y.F.,Wang, Z.Y.,Ni, Y.,Song, H.X. (deposition date: 2021-08-24, release date: 2022-08-31, Last modification date: 2023-11-29)

• Primary citation: Song, H.,Wu, J.,Tang, Y.,Dai, Y.,Xiang, X.,Li, Y.,Wu, L.,Wu, J.,Liang, Y.,Xing, Y.,Yan, N.,Li, Y.,Wang, Z.,Xiao, S.,Li, J.,Zheng, D.,Chen, X.,Fang, H.,Ye, C.,Ma, Y.,Wu, Y.,Wu, W.,Li, J.,Zhang, S.,Lu, M.; Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties.; Sci Transl Med, 15:eabn9155-eabn9155, 2023; PubMed: 37018419; DOI: 10.1126/scitranslmed.abn9155

Experimental method

X-RAY DIFFRACTION (2.02 Å)