7V6X

Crystal structure of HPPD complexed with Y18556

Summary for 7V6X

Entry DOI	10.2210/pdb7v6x/pdb
Descriptor	4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 5-methyl-3-[(2-methylphenyl)methyl]-6-[(1~{R},2~{S})-2-oxidanyl-6-oxidanylidene-cyclohexyl]carbonyl-1,2,3-benzotriazin-4-one, ... (4 entities in total)
Functional Keywords	complex, inhibitor, oxidoreductase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	1
Total formula weight	46417.11
Authors	Lin, H.Y.,Yang, G.F. (deposition date: 2021-08-20, release date: 2022-08-24, Last modification date: 2023-11-29)
Primary citation	Yan, Y.C.,Wu, W.,Huang, G.Y.,Yang, W.C.,Chen, Q.,Qu, R.Y.,Lin, H.Y.,Yang, G.F. Pharmacophore-Oriented Discovery of Novel 1,2,3-Benzotriazine-4-one Derivatives as Potent 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. J.Agric.Food Chem., 70:6644-6657, 2022 Cited by PubMed: 35618678 DOI: 10.1021/acs.jafc.2c01507 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation