7V4M
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Summary for 7V4M
Entry DOI | 10.2210/pdb7v4m/pdb |
Descriptor | Beta-hydroxylase, 2-OXOGLUTARIC ACID, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | caprazamycin, mray, beta-hydroxylase, antibiotic |
Biological source | Streptomyces sp. MK730-62F2 |
Total number of polymer chains | 1 |
Total formula weight | 21482.62 |
Authors | Li, T.L.,Saeid, M.Z. (deposition date: 2021-08-13, release date: 2022-02-23, Last modification date: 2023-11-29) |
Primary citation | Zadeh, S.M.,Chen, M.H.,Wang, Z.C.,Astani, E.K.,Lo, I.W.,Lin, K.H.,Hsu, N.S.,Adhikari, K.,Lyu, S.Y.,Tsai, H.Y.,Terasawa, Y.,Yabe, M.,Yamamoto, K.,Ichikawa, S.,Li, T.L. beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin Commun Chem, 5:87-, 2022 Cited by DOI: 10.1038/s42004-022-00703-6PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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