7V2A

SARS-CoV-2 Spike trimer in complex with XG014 Fab

7V2A の概要

• エントリーDOI: 10.2210/pdb7v2a/pdb
• EMDBエントリー: 31639
• 分子名称: Spike glycoprotein, The light chain of XG014 Fab, The heavy chain of XG014, ... (4 entities in total)
• 機能のキーワード: a neutralizing antibody bound with the s protein of sars-cov-2, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 552158.74

構造登録者

Wang, K.,Wang, X.,Pan, L. (登録日: 2021-08-07, 公開日: 2021-10-20, 最終更新日: 2022-07-06)

• 主引用文献: Liu, Z.,Xu, W.,Chen, Z.,Fu, W.,Zhan, W.,Gao, Y.,Zhou, J.,Zhou, Y.,Wu, J.,Wang, Q.,Zhang, X.,Hao, A.,Wu, W.,Zhang, Q.,Li, Y.,Fan, K.,Chen, R.,Jiang, Q.,Mayer, C.T.,Schoofs, T.,Xie, Y.,Jiang, S.,Wen, Y.,Yuan, Z.,Wang, K.,Lu, L.,Sun, L.,Wang, Q.; An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.; Protein Cell, 13:655-675, 2022; PubMed: 34554412; DOI: 10.1007/s13238-021-00871-6

実験手法

ELECTRON MICROSCOPY (3.4 Å)