7UZC
Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, M8a-34
Summary for 7UZC
Entry DOI | 10.2210/pdb7uzc/pdb |
Descriptor | Spike protein S1, M8a-34 Fab heavy chain, M8a-34 Fab light chain, ... (6 entities in total) |
Functional Keywords | immune system, neutralizing antibody, immune system-viral protein complex, immune system/viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 6 |
Total formula weight | 152574.29 |
Authors | Fan, C.,Bjorkman, P.J. (deposition date: 2022-05-08, release date: 2023-01-11, Last modification date: 2023-10-25) |
Primary citation | Fan, C.,Cohen, A.A.,Park, M.,Hung, A.F.,Keeffe, J.R.,Gnanapragasam, P.N.P.,Lee, Y.E.,Gao, H.,Kakutani, L.M.,Wu, Z.,Kleanthous, H.,Malecek, K.E.,Williams, J.C.,Bjorkman, P.J. Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes. Immunity, 55:2419-2435.e10, 2022 Cited by PubMed: 36370711DOI: 10.1016/j.immuni.2022.10.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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