7UYI

Crystal structure of the computationally optimized broadly reactive H1 influenza hemagglutinin P1

7UYI の概要

• エントリーDOI: 10.2210/pdb7uyi/pdb
• 分子名称: COBRA P1 HA, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: hemagglutinin, virus entry, antigenic, viral protein
• 由来する生物種: Influenza A virus
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 356482.86

構造登録者

Dzimianski, J.V.,DuBois, R.M. (登録日: 2022-05-06, 公開日: 2023-04-19, 最終更新日: 2024-05-01)

• 主引用文献: Dzimianski, J.V.,Han, J.,Sautto, G.A.,O'Rourke, S.M.,Cruz, J.M.,Pierce, S.R.,Ecker, J.W.,Carlock, M.A.,Nagashima, K.A.,Mousa, J.J.,Ross, T.M.,Ward, A.B.,DuBois, R.M.; Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine.; Commun Biol, 6:454-454, 2023; PubMed: 37185989; DOI: 10.1038/s42003-023-04793-3

実験手法

X-RAY DIFFRACTION (3 Å)