7UX8

Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH and L-Tyrosine bound at 1.4 A resolution (P212121 - form II)

7UX8 の概要

• エントリーDOI: 10.2210/pdb7ux8/pdb
• 関連するPDBエントリー: 7UX6 7UX7
• 分子名称: MfnG, S-ADENOSYL-L-HOMOCYSTEINE, TYROSINE, ... (5 entities in total)
• 機能のキーワード: o-methyltransferase, o-methyl-tyrosine, marformycin synthesis, sam-dependent methyltransferase, transferase
• 由来する生物種: Streptomyces drozdowiczii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85215.69

構造登録者

Miller, M.D.,Wu, K.-L.,Xu, W.,Xiao, H.,Philips Jr., G.N. (登録日: 2022-05-05, 公開日: 2022-09-28, 最終更新日: 2023-10-18)

• 主引用文献: Wu, K.L.,Moore, J.A.,Miller, M.D.,Chen, Y.,Lee, C.,Xu, W.,Peng, Z.,Duan, Q.,Phillips Jr., G.N.,Uribe, R.A.,Xiao, H.; Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid.; Protein Sci., 31:e4443-e4443, 2022; PubMed: 36173166; DOI: 10.1002/pro.4443

実験手法

X-RAY DIFFRACTION (1.4 Å)