7UVF
Crystal structure of ZED8 Fab complex with CD8 alpha
Summary for 7UVF
Entry DOI | 10.2210/pdb7uvf/pdb |
Descriptor | T-cell surface glycoprotein CD8 alpha chain, Immunoglobulin heavy chain, Immunoglobulin light chain, ... (6 entities in total) |
Functional Keywords | imaging, cd8, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 122837.79 |
Authors | Yu, C.,Davies, C.,Koerber, J.T.,Williams, S. (deposition date: 2022-05-01, release date: 2022-10-12, Last modification date: 2024-04-03) |
Primary citation | Ogasawara, A.,Kiefer, J.R.,Gill, H.,Chiang, E.,Sriraman, S.,Ferl, G.Z.,Ziai, J.,Bohorquez, S.S.,Guelman, S.,Wang, X.,Yang, J.,Phan, M.M.,Nguyen, V.,Chung, S.,Yu, C.,Tinianow, J.,Waaijer, S.J.H.,De Crespigny, A.,Marik, J.,Boswell, C.A.,Zabka, T.,Staflin, K.,Williams, S.P. Preclinical development of ZED8, an 89 Zr immuno-PET reagent for monitoring tumor CD8 status in patients undergoing cancer immunotherapy. Eur J Nucl Med Mol Imaging, 50:287-301, 2023 Cited by PubMed: 36271158DOI: 10.1007/s00259-022-05968-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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