7UV6

Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and scaffold duplex (21mer) containing the cognate REPE54 sequence and an insert duplex (10mer) with guest TAMRA-labelled thymine and G-C rich sequence.

Summary for 7UV6

• Entry DOI: 10.2210/pdb7uv6/pdb
• Related: 7rva 7u6k 7u7o 7ufx 7uog 7ur0
• Descriptor: DNA (5'-D(*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*G)-3'), Replication initiation protein, ... (7 entities in total)
• Functional Keywords: replication initiator repe complex co-crystal, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 5
• Total formula weight: 49848.90

Authors

Orun, A.R.,Snow, C.D. (deposition date: 2022-04-29, release date: 2023-05-03, Last modification date: 2024-05-01)

• Primary citation: Orun, A.R.,Shields, E.T.,Dmytriw, S.,Vajapayajula, A.,Slaughter, C.K.,Snow, C.D.; Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds.; Acs Nano, 17:13110-13120, 2023; PubMed: 37407546; DOI: 10.1021/acsnano.2c07282

Experimental method

X-RAY DIFFRACTION (2.72 Å)