7UUX

ATP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination

Summary for 7UUX

• Entry DOI: 10.2210/pdb7uux/pdb
• Descriptor: Cyclic GMP-AMP synthase, Palindromic DNA18, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: transferase-dna complex, transferase/dna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 6
• Total formula weight: 108528.76

Authors

Wu, S.,Gabelli, S.B.,Sohn, J. (deposition date: 2022-04-29, release date: 2023-05-03, Last modification date: 2024-05-22)

• Primary citation: Wu, S.,Gabelli, S.B.,Sohn, J.; The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS; Nat Commun, 15:4012-, 2024; DOI: 10.1038/s41467-024-48365-3

Experimental method

X-RAY DIFFRACTION (2.26 Å)