7UTC

Crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus with NADP and transition-state analogue inhibitor DMSO

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7UTC の概要

• エントリーDOI: 10.2210/pdb7utc/pdb
• 分子名称: Secondary-alcohol dehydrogenase, ZINC ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: secondary alcohol dehydrogenases, transition-state analogue inhibitor, dmso, nadp, oxidoreductase
• 由来する生物種: Thermoanaerobacter pseudethanolicus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 156621.15

構造登録者

Dinh, T.,Phillips, R. (登録日: 2022-04-26, 公開日: 2022-05-04, 最終更新日: 2023-10-18)

• 主引用文献: Dinh, T.,Rahn, K.T.,Phillips, R.S.; Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.; Proteins, 90:1570-1583, 2022; PubMed: 35357038; DOI: 10.1002/prot.26339

実験手法

X-RAY DIFFRACTION (1.85 Å)