7UR4
Cryo-EM Structure of the Neutralizing Antibody MPV467 in Complex with Prefusion Human Metapneumovirus F Glycoprotein
Summary for 7UR4
Entry DOI | 10.2210/pdb7ur4/pdb |
EMDB information | 26704 |
Descriptor | Fusion glycoprotein F0, MPV467 Fab Heavy chain, MPV467 Fab Light chain, ... (5 entities in total) |
Functional Keywords | neutralizing antibody, fusion protein, metapneumovirus, viral protein-immune system complex, viral protein/immune system |
Biological source | Human metapneumovirus More |
Total number of polymer chains | 9 |
Total formula weight | 324493.77 |
Authors | Rush, S.A.,McLellan, J.S. (deposition date: 2022-04-21, release date: 2022-06-08, Last modification date: 2022-06-29) |
Primary citation | Banerjee, A.,Huang, J.,Rush, S.A.,Murray, J.,Gingerich, A.D.,Royer, F.,Hsieh, C.L.,Tripp, R.A.,McLellan, J.S.,Mousa, J.J. Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus. Proc.Natl.Acad.Sci.USA, 119:e2203326119-e2203326119, 2022 Cited by PubMed: 35696580DOI: 10.1073/pnas.2203326119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
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