7UPL
SARS-Cov2 Omicron varient S protein structure in complex with neutralizing monoclonal antibody 002-S21F2
Summary for 7UPL
Entry DOI | 10.2210/pdb7upl/pdb |
EMDB information | 26669 |
Descriptor | Spike glycoprotein, mAB 002-S21F2 light chain, mAb 002-S21F2 heavy chain, ... (5 entities in total) |
Functional Keywords | sars-cov2, 6p, spike protein, immune complex, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 7 |
Total formula weight | 573412.73 |
Authors | Patel, A.,Ortlund, E. (deposition date: 2022-04-15, release date: 2022-08-10, Last modification date: 2024-10-09) |
Primary citation | Kumar, S.,Patel, A.,Lai, L.,Chakravarthy, C.,Valanparambil, R.,Reddy, E.S.,Gottimukkala, K.,Davis-Gardner, M.E.,Edara, V.V.,Linderman, S.,Nayak, K.,Dixit, K.,Sharma, P.,Bajpai, P.,Singh, V.,Frank, F.,Cheedarla, N.,Verkerke, H.P.,Neish, A.S.,Roback, J.D.,Mantus, G.,Goel, P.K.,Rahi, M.,Davis, C.W.,Wrammert, J.,Godbole, S.,Henry, A.R.,Douek, D.C.,Suthar, M.S.,Ahmed, R.,Ortlund, E.,Sharma, A.,Murali-Krishna, K.,Chandele, A. Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody. Sci Adv, 8:eadd2032-eadd2032, 2022 Cited by PubMed: 36197988DOI: 10.1126/sciadv.add2032 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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