7UOR
Crystal structure of cytochrome P450 enzyme CYP119 in complex with methyliridium(III) mesoporphyrin.
Summary for 7UOR
| Entry DOI | 10.2210/pdb7uor/pdb |
| Descriptor | Cytochrome, methyliridium(III) mesoporphyrin, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
| Functional Keywords | cytochrome p450 iridium, oxidoreductase |
| Biological source | Sulfolobus acidocaldarius |
| Total number of polymer chains | 6 |
| Total formula weight | 276353.35 |
| Authors | Pereira, J.H.,Bloomer, B.J.,Hartwig, J.F.,Adams, P.D. (deposition date: 2022-04-13, release date: 2023-02-22, Last modification date: 2023-10-25) |
| Primary citation | Bloomer, B.J.,Natoli, S.N.,Garcia-Borras, M.,Pereira, J.H.,Hu, D.B.,Adams, P.D.,Houk, K.N.,Clark, D.S.,Hartwig, J.F. Mechanistic and structural characterization of an iridium-containing cytochrome reveals kinetically relevant cofactor dynamics Nat Catal, 6:39-51, 2023 Cited by DOI: 10.1038/s41929-022-00899-9PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.16 Å) |
Structure validation
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