7UOR

Crystal structure of cytochrome P450 enzyme CYP119 in complex with methyliridium(III) mesoporphyrin.

7UOR の概要

• エントリーDOI: 10.2210/pdb7uor/pdb
• 分子名称: Cytochrome, methyliridium(III) mesoporphyrin, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: cytochrome p450 iridium, oxidoreductase
• 由来する生物種: Sulfolobus acidocaldarius
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 276353.35

構造登録者

Pereira, J.H.,Bloomer, B.J.,Hartwig, J.F.,Adams, P.D. (登録日: 2022-04-13, 公開日: 2023-02-22, 最終更新日: 2023-10-25)

• 主引用文献: Bloomer, B.J.,Natoli, S.N.,Garcia-Borras, M.,Pereira, J.H.,Hu, D.B.,Adams, P.D.,Houk, K.N.,Clark, D.S.,Hartwig, J.F.; Mechanistic and structural characterization of an iridium-containing cytochrome reveals kinetically relevant cofactor dynamics; Nat Catal, 6:39-51, 2023; DOI: 10.1038/s41929-022-00899-9

実験手法

X-RAY DIFFRACTION (3.16 Å)