7UOJ

The CryoEM structure of N49-P9.6-FR3 and PGT121 Fabs in complex with BG505 SOSIP.664

Summary for 7UOJ

• Entry DOI: 10.2210/pdb7uoj/pdb
• EMDB information: 26648
• Descriptor: Envelope glycoprotein gp120, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: hiv-1, envelope trimer, gp120, gp41, viral entry, type-1 membrane fusion glycoprotein, n49p9.6-fr3, pgt121, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 18
• Total formula weight: 521667.08

Authors

Nguyen, D.N.,Tolbert, W.D.,Pazgier, M. (deposition date: 2022-04-13, release date: 2023-05-03, Last modification date: 2024-10-16)

• Primary citation: Nguyen, D.N.,Tolbert, W.D.,Pazgier, M.; The structure of N49-P9.6-FR3 and PGT121 Fabs in complex with BG505 SOSIP; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.02 Å)