7UN7

DNA Polymerase lambda in complex with a 1nt microhomology substrate

Summary for 7UN7

• Entry DOI: 10.2210/pdb7un7/pdb
• Descriptor: DNA polymerase lambda, 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*GP*CP*AP*GP*T)-3'), ... (11 entities in total)
• Functional Keywords: replication
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 44271.13

Authors

Jamsen, J.A. (deposition date: 2022-04-09, release date: 2023-03-29, Last modification date: 2023-10-25)

• Primary citation: Chandramouly, G.,Jamsen, J.,Borisonnik, N.,Tyagi, M.,Calbert, M.L.,Tredinnick, T.,Ozdemir, A.Y.,Kent, T.,Demidova, E.V.,Arora, S.,Wilson, S.H.,Pomerantz, R.T.; Pol lambda promotes microhomology-mediated end-joining.; Nat.Struct.Mol.Biol., 30:107-114, 2023; PubMed: 36536104; DOI: 10.1038/s41594-022-00895-4

Experimental method

X-RAY DIFFRACTION (2.04 Å)