7UKL

Cryo-EM structure of Antibody 12-16 in complex with prefusion SARS-CoV-2 Spike glycoprotein

7UKL の概要

• エントリーDOI: 10.2210/pdb7ukl/pdb
• EMDBエントリー: 26583 26584
• 分子名称: 12-16 Fab Light Chain, Spike glycoprotein, 12-16 Fab Heavy Chain, ... (4 entities in total)
• 機能のキーワード: neutralizing antibody, viral fusion protein, sars-cov-2, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 513055.49

構造登録者

Casner, R.G.,Shapiro, L. (登録日: 2022-04-01, 公開日: 2023-10-04, 最終更新日: 2023-10-25)

• 主引用文献: Liu, L.,Casner, R.G.,Guo, Y.,Wang, Q.,Iketani, S.,Chan, J.F.,Yu, J.,Dadonaite, B.,Nair, M.S.,Mohri, H.,Reddem, E.R.,Yuan, S.,Poon, V.K.,Chan, C.C.,Yuen, K.Y.,Sheng, Z.,Huang, Y.,Bloom, J.D.,Shapiro, L.,Ho, D.D.; Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking.; Immunity, 56:2442-, 2023; PubMed: 37776849; DOI: 10.1016/j.immuni.2023.09.003

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