7UJS
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B in complex with ADP
Replaces: 6XDUSummary for 7UJS
Entry DOI | 10.2210/pdb7ujs/pdb |
Related | 6x5g |
Descriptor | Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, NMDA 2B, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | camkii, kinase, human, camk2a, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 33730.43 |
Authors | Ozden, C.,Santos, N.J.,Stratton, M.M.,Garman, S.C. (deposition date: 2022-03-31, release date: 2022-04-13, Last modification date: 2023-10-18) |
Primary citation | Ozden, C.,Sloutsky, R.,Mitsugi, T.,Santos, N.,Agnello, E.,Gaubitz, C.,Foster, J.,Lapinskas, E.,Esposito, E.A.,Saneyoshi, T.,Kelch, B.A.,Garman, S.C.,Hayashi, Y.,Stratton, M.M. CaMKII binds both substrates and activators at the active site. Cell Rep, 40:111064-111064, 2022 Cited by PubMed: 35830796DOI: 10.1016/j.celrep.2022.111064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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