7UID
Thyclotides peptide nucleic acid in complex with DNA
Summary for 7UID
| Entry DOI | 10.2210/pdb7uid/pdb |
| Descriptor | DNA (5'-D(*GP*AP*TP*GP*TP*GP*AP*TP*A)-3'), Thyclotide, ZINC ION, ... (5 entities in total) |
| Functional Keywords | thyclotides, peptide nucleic acid, pna, peptide nucleic acid-dna complex, dna-peptide nucleic acid complex, dna/peptide nucleic acid |
| Biological source | synthetic construct More |
| Total number of polymer chains | 4 |
| Total formula weight | 12114.43 |
| Authors | Botos, I.,Appella, D.H. (deposition date: 2022-03-29, release date: 2023-04-05, Last modification date: 2023-11-15) |
| Primary citation | Zheng, H.,Clausse, V.,Amarasekara, H.,Mazur, S.J.,Botos, I.,Appella, D.H. Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids. Jacs Au, 3:1952-1964, 2023 Cited by PubMed: 37502163DOI: 10.1021/jacsau.3c00198 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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