7UGG
Cryo-EM structure of TRPV3 in complex with the anesthetic dyclonine
Summary for 7UGG
Entry DOI | 10.2210/pdb7ugg/pdb |
EMDB information | 26488 |
Descriptor | Transient receptor potential cation channel subfamily V member 3, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Dyclonine, ... (5 entities in total) |
Functional Keywords | transient receptor potential v family member 3, trp, channel, closed, trpv3, anesthetic, dyclonine, membrane protein |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 4 |
Total formula weight | 389740.02 |
Authors | Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. (deposition date: 2022-03-24, release date: 2022-06-08, Last modification date: 2024-02-14) |
Primary citation | Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine. Nat Commun, 13:2795-2795, 2022 Cited by PubMed: 35589741DOI: 10.1038/s41467-022-30537-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.16 Å) |
Structure validation
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