7UGG

Cryo-EM structure of TRPV3 in complex with the anesthetic dyclonine

7UGG の概要

• エントリーDOI: 10.2210/pdb7ugg/pdb
• EMDBエントリー: 26488
• 分子名称: Transient receptor potential cation channel subfamily V member 3, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Dyclonine, ... (5 entities in total)
• 機能のキーワード: transient receptor potential v family member 3, trp, channel, closed, trpv3, anesthetic, dyclonine, membrane protein
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 389740.02

構造登録者

Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. (登録日: 2022-03-24, 公開日: 2022-06-08, 最終更新日: 2024-02-14)

• 主引用文献: Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I.; Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine.; Nat Commun, 13:2795-2795, 2022; PubMed: 35589741; DOI: 10.1038/s41467-022-30537-8

実験手法

ELECTRON MICROSCOPY (3.16 Å)