7UF5

RibB from Vibrio cholera bound with intermediate 2 in the reaction cycle and the products DHBP and formate

7UF5 の概要

• エントリーDOI: 10.2210/pdb7uf5/pdb
• 分子名称: 3,4-dihydroxy-2-butanone 4-phosphate synthase, (2R)-2-(dihydroxymethyl)-2-hydroxy-3-oxobutyl dihydrogen phosphate, (2R)-2-hydroxy-3-oxobutyl dihydrogen phosphate, ... (6 entities in total)
• 機能のキーワード: ribb, riboflavin, 3, 4-dihydroxy-2-butanone 4-phosphate synthase, lyase
• 由来する生物種: Vibrio cholerae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24105.11

構造登録者

Kenjic, N.,Meneely, K.M.,Lamb, A.L. (登録日: 2022-03-22, 公開日: 2022-07-20, 最終更新日: 2023-10-18)

• 主引用文献: Kenjic, N.,Meneely, K.M.,Wherritt, D.J.,Denler, M.C.,Jackson, T.A.,Moran, G.R.,Lamb, A.L.; Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis.; J.Am.Chem.Soc., 144:12769-12780, 2022; PubMed: 35802469; DOI: 10.1021/jacs.2c03376

実験手法

X-RAY DIFFRACTION (2.1 Å)