7UAK
Structure of recombinantly assembled A53E alpha-synuclein fibrils
Summary for 7UAK
Entry DOI | 10.2210/pdb7uak/pdb |
EMDB information | 26427 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | alpha-synuclein fibrils, a53e mutant, cryo-em structure, structural protein, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 87204.88 |
Authors | |
Primary citation | Sun, C.,Zhou, K.,DePaola IV, P.,Shin, W.S.,Hillyer, T.,Sawaya, M.R.,Zhu, R.,Peng, C.,Zhou, Z.H.,Jiang, L. Cryo-EM structure of amyloid fibril formed by alpha-synuclein hereditary A53E mutation reveals a distinct protofilament interface. J.Biol.Chem., 299:104566-104566, 2023 Cited by PubMed: 36871760DOI: 10.1016/j.jbc.2023.104566 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.38 Å) |
Structure validation
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