7UA4
Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin
This is a non-PDB format compatible entry.
Summary for 7UA4
Entry DOI | 10.2210/pdb7ua4/pdb |
EMDB information | 26414 |
Descriptor | Ryanodine receptor 2, Peptidyl-prolyl cis-trans isomerase FKBP1B, Calmodulin-1, ... (7 entities in total) |
Functional Keywords | ryanodine receptor 2, calcium channel, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 2380556.02 |
Authors | |
Primary citation | Miotto, M.C.,Weninger, G.,Dridi, H.,Yuan, Q.,Liu, Y.,Wronska, A.,Melville, Z.,Sittenfeld, L.,Reiken, S.,Marks, A.R. Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8:eabo1272-eabo1272, 2022 Cited by PubMed: 35857850DOI: 10.1126/sciadv.abo1272 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.93 Å) |
Structure validation
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