7U9D

Crystal Structure of Human Phosphatidylcholine Transfer Protein in Complex with PC(16:0/20:4)

7U9D の概要

• エントリーDOI: 10.2210/pdb7u9d/pdb
• 分子名称: Phosphatidylcholine transfer protein, [(2~{R})-1-hexadecanoyloxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propan-2-yl] (5~{Z},8~{Z},11~{Z},14~{Z})-icosa-5,8,11,14-tetraenoate, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: phosphatidylcholine transfer protein, pc(16:0/20:4), complex, ligand, lipid binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25746.49

構造登録者

Druzak, S.A. (登録日: 2022-03-10, 公開日: 2023-04-12, 最終更新日: 2024-04-24)

• 主引用文献: Druzak, S.A.,Tardelli, M.,Mays, S.G.,El Bejjani, M.,Mo, X.,Maner-Smith, K.M.,Bowen, T.,Cato, M.L.,Tillman, M.C.,Sugiyama, A.,Xie, Y.,Fu, H.,Cohen, D.E.,Ortlund, E.A.; Ligand dependent interaction between PC-TP and PPAR delta mitigates diet-induced hepatic steatosis in male mice.; Nat Commun, 14:2748-2748, 2023; PubMed: 37173315; DOI: 10.1038/s41467-023-38010-w

実験手法

X-RAY DIFFRACTION (2.18 Å)