7U8S
Crystal Structure of KPC-2 with compound 2
Summary for 7U8S
Entry DOI | 10.2210/pdb7u8s/pdb |
Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, 3-fluoro-N-[(1R,3S)-3-(1H-tetrazol-5-yl)-2,3-dihydro-1H-inden-1-yl]benzamide (3 entities in total) |
Functional Keywords | beta-lactamase, tetrazole, inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 28414.96 |
Authors | Akhtar, A.,Chen, Y. (deposition date: 2022-03-09, release date: 2023-03-22, Last modification date: 2023-10-25) |
Primary citation | DeFrees, K.,Cambeis, E.M.,Chen, Y.,Renslo, A.R. Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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