7U8J

Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83

7U8J の概要

• エントリーDOI: 10.2210/pdb7u8j/pdb
• 分子名称: Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, Antibody Fab light chain, ... (4 entities in total)
• 機能のキーワード: universal vaccine design, chimeric influenza hemagglutinin, ha trimer interface and stem, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 104591.69

構造登録者

Zhu, X.,Wilson, I.A. (登録日: 2022-03-08, 公開日: 2022-06-08, 最終更新日: 2023-10-18)

• 主引用文献: Zhu, X.,Han, J.,Sun, W.,Puente-Massaguer, E.,Yu, W.,Palese, P.,Krammer, F.,Ward, A.B.,Wilson, I.A.; Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.; Proc.Natl.Acad.Sci.USA, 119:e2200821119-e2200821119, 2022; PubMed: 35594401; DOI: 10.1073/pnas.2200821119

実験手法

X-RAY DIFFRACTION (4.9 Å)