7U8A

Product of 14mer primer with activated G monomer diastereomer 2

Summary for 7U8A

• Entry DOI: 10.2210/pdb7u8a/pdb
• Descriptor: RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3'), 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: rna duplex, phosphorothioate, non-enzymatic rna extension, rna
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 10598.44

Authors

Fang, Z.,Szostak, J.W. (deposition date: 2022-03-08, release date: 2023-03-15, Last modification date: 2024-04-17)

• Primary citation: Fang, Z.,Pazienza, L.T.,Zhang, J.,Tam, C.P.,Szostak, J.W.; Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.; J.Am.Chem.Soc., 2024; PubMed: 38579124; DOI: 10.1021/jacs.4c00323

Experimental method

X-RAY DIFFRACTION (2.1 Å)