7U6U
Structure of an intellectual disability-associated ornithine decarboxylase variant G84R in complex with PLP
Summary for 7U6U
Entry DOI | 10.2210/pdb7u6u/pdb |
Descriptor | Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total) |
Functional Keywords | ornithine decarboxylase, intellectual disability-associated variant, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 95177.79 |
Authors | Zhou, X.E.,Schultz, C.R.,Powell, K.S.,Henrickson, A.,Lamp, J.,Brunzelle, J.S.,Demeler, B.,Vega, I.E.,Bachmann, A.S.,Melcher, K. (deposition date: 2022-03-06, release date: 2022-10-19, Last modification date: 2023-10-18) |
Primary citation | Zhou, X.E.,Schultz, C.R.,Suino Powell, K.,Henrickson, A.,Lamp, J.,Brunzelle, J.S.,Demeler, B.,Vega, I.E.,Bachmann, A.S.,Melcher, K. Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R. Acs Omega, 7:34665-34675, 2022 Cited by PubMed: 36188294DOI: 10.1021/acsomega.2c04702 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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