7U0C
Crystal structure of broadly neutralizing antibody HEPC3.4
Summary for 7U0C
Entry DOI | 10.2210/pdb7u0c/pdb |
Descriptor | HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain (2 entities in total) |
Functional Keywords | hcv glycoprotein, broadly neutralizing antibodies, antiviral protein, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 145965.69 |
Authors | Flyak, A.I.,Bjorkman, P.J. (deposition date: 2022-02-17, release date: 2022-06-08, Last modification date: 2023-10-18) |
Primary citation | Bozhanova, N.G.,Flyak, A.I.,Brown, B.P.,Ruiz, S.E.,Salas, J.,Rho, S.,Bombardi, R.G.,Myers, L.,Soto, C.,Bailey, J.R.,Crowe Jr., J.E.,Bjorkman, P.J.,Meiler, J. Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nat Commun, 13:3178-3178, 2022 Cited by PubMed: 35676279DOI: 10.1038/s41467-022-30865-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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