7U0C

Crystal structure of broadly neutralizing antibody HEPC3.4

Summary for 7U0C

Entry DOI	10.2210/pdb7u0c/pdb
Descriptor	HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain (2 entities in total)
Functional Keywords	hcv glycoprotein, broadly neutralizing antibodies, antiviral protein, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	145965.69
Authors	Flyak, A.I.,Bjorkman, P.J. (deposition date: 2022-02-17, release date: 2022-06-08, Last modification date: 2023-10-18)
Primary citation	Bozhanova, N.G.,Flyak, A.I.,Brown, B.P.,Ruiz, S.E.,Salas, J.,Rho, S.,Bombardi, R.G.,Myers, L.,Soto, C.,Bailey, J.R.,Crowe Jr., J.E.,Bjorkman, P.J.,Meiler, J. Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nat Commun, 13:3178-3178, 2022 Cited by PubMed: 35676279 DOI: 10.1038/s41467-022-30865-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation