7TXG
Structure of the Class II Fructose-1,6-Bisphosphatase from Francisella tularensis with native Mn++ divalent cation and partially occupied product F6P
Summary for 7TXG
| Entry DOI | 10.2210/pdb7txg/pdb |
| Descriptor | Fructose-1,6-bisphosphatase, GLYCEROL, MANGANESE (II) ION, ... (5 entities in total) |
| Functional Keywords | class ii fbpases; fructose-1, 6-bisphosphatase; francisella tularensis; mycobacterium tuberculosis; gluconeogenesis; antibiotic targets, hydrolase |
| Biological source | Francisella tularensis |
| Total number of polymer chains | 4 |
| Total formula weight | 149629.95 |
| Authors | Abad-Zapatero, C.,Selezneva, A.I.,Harding, L.N.M.,Movahedzadeh, F. (deposition date: 2022-02-09, release date: 2023-06-28, Last modification date: 2023-10-25) |
| Primary citation | Selezneva, A.I.,Harding, L.N.M.,Gutka, H.J.,Movahedzadeh, F.,Abad-Zapatero, C. New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class. Plos One, 18:e0274723-e0274723, 2023 Cited by PubMed: 37352301DOI: 10.1371/journal.pone.0274723 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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